Now revealing
LITFULO

The first and only FDA-approved
treatment for both adults and adolescents as
young as 12 with severe alopecia areata.

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VideoId: 6338511487112: /assets/images/video-posters/media_18f326b5cbffe6f92c0ce3e4565e8c45ea883a422.jpeg: Woman with alopecia areata before and after
In just under 6 months, 23% of people taking LITFULO in the clinical study saw 80% or more scalp hair coverage (vs 1.6% on placebo) and 13.4% of people taking LITFULO saw 90% or more scalp hair coverage (vs 1.5% on placebo). Individual results may vary.
Adolescent Male with alopecia areata looking forward

LITFULO, a once-daily pill, is here

LITFULO is a once-daily prescription pill for severe alopecia areata in both adults and adolescents as young as 12.

Some people taking Litfulo ™ (ritlecitinib) saw significant hair regrowth that covered 80% or more of their scalp in just under 6 months. See safety info.

Some people taking Litfulo ™ (ritlecitinib) saw significant hair regrowth that covered 80% or more of their scalp in just under 6 months. See safety info.

In a 48-week, randomized, double-blind, and placebo-controlled clinical study, participants (261 people, ages 12+, who had lost at least half of their scalp hair due to alopecia areata) took either LITFULO or placebo (an inactive pill). Safety and effectiveness have not been studied in people under 12 years of age. Results were measured at 24 weeks. Find out more information about the study.

LITFULO may cause serious side effects, including:

serious infections; increased risk of death; cancer and immune system problems; increased risk of major cardiovascular events; blood clots; allergic reactions; and changes in certain laboratory test results. For more information, talk to your doctor or learn more about the most important information about LITFULO.

Results with LITFULO

Significant hair regrowth was seen
in just under 6 months

Nearly 25% of adults and adolescents taking LITFULO saw significant hair regrowth that covered 80% or more of their scalp (vs 1.6% on placebo), in just under 6 months. Additionally, 13.4% of people taking LITFULO saw 90% or more scalp hair coverage (vs 1.5% on placebo).

In 23% of adults and adolescents taking LITFULO in the clinical study.

Before & After Photos

Clinical study photos show an example of hair regrowth observed on the scalp of an actual adult or adolescent patient with alopecia areata. Individual results may vary.

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The most common side effects of LITFULO include:

headache; diarrhea; acne; rash; hives; inflamed hair pores (folliculitis); fever; eczema; dizziness; shingles; decreased red blood cell counts; and mouth sores, redness and swelling of the lining of your mouth. These are not all of the possible side effects of LITFULO. For more information, talk to your doctor or learn more about the most important information about LITFULO.

Getting to know LITFULO

Woman with alopecia areata smiling

Getting to know LITFULO

Litfulo ™ (ritlecitinib) is FDA approved for both adults & adolescents as young as 12. See safety info.
LITFULO is the only FDA-approved treatment for adolescents (ages 12-17) with severe alopecia areata.

Some patients taking Litfulo ™ (ritlecitinib) saw significant hair regrowth in just under 6 months. See safety info.

Some patients taking Litfulo ™ (ritlecitinib) saw 80% or more scalp hair coverage. See safety info.

In just under 6 months, nearly 25% of adults and adolescents taking LITFULO saw significant hair regrowth that covered 80% or more of their scalp.§
§In 23% of adults and adolescents taking LITFULO vs 1.6% taking placebo in the clinical study.

How LITFULO Works

A look at LITFULO and alopecia areata

Alopecia areata is an autoimmune disease. In people with alopecia areata, their own immune system mistakenly attacks hair follicles at the root, causing hair to fall out. Typically, hair is protected from an immune system attack, but in alopecia areata, this protection is lost.

LITFULO is a prescription medicine that works inside the body to treat severe alopecia areata. Take a closer look at how LITFULO works below.

Alopecia areata mechanism of disease.
In alopecia areata, immune cells mistakenly receive signals to swarm and attack the hair follicle, leading to inflammation at the hair follicle and causing hair loss.
Litfulo ™ (ritlecitinib) mechanism of action
These signals are sent from proteins deep within the immune cells.
Litfulo ™ (ritlecitinib) mechanism of action
LITFULO binds to select proteins within immune cells and blocks their signaling process …
Litfulo ™ (ritlecitinib) mechanism of action
… to decrease the number of immune cells attacking the hair follicle.
For illustrative purposes.
It’s not currently known how blocking specific proteins can affect alopecia areata.
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Savings & Support

Pay as little as $0
for LITFULO||

Check out the Copay Savings Card
If eligible, sign up for savings in 2 simple steps, or get a Copay Savings Card texted to you now. Text SAVEWEB to 82000.

Get to know LITFULO
Sign up to receive information about LITFULO, resources to support your treatment journey, and helpful tips.

Learn about financial support
Through Pfizer Dermatology Patient Access™, you can receive personalized, live support from a Patient Support Representative, a review of insurance coverage, and financial assistance resources.

Explore Your Options

Man with alopecia areata

Talking to a Doctor

A disease that
deserves discussion

Get the conversation going!

It’s important to talk openly with your dermatologist about your hair history and how alopecia areata affects your daily life. Create a personalized Doctor Discussion Guide to share at your next appointment and ask your dermatologist if LITFULO might be right for you.

Download the Guide

Looking for a dermatologist?

Finding a dermatologist near you is now easier than ever with the Find a Dermatologist tool.

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Capture your progress

While taking LITFULO, be sure to take photos over time to track any changes that you see. Share these photos with your dermatologist, so they can see the full picture of your progress. You may find that these photos are inspirational—a reminder of why you’re on this journey.

Here are some tips on capturing your very own “before and after” photos.

Prior to starting treatment, take your “before” shot
Pick a photo-friendly location (well-lit, clean background) and use it each time
Try to capture the same angles of your scalp at the same time every month
Schedule a monthly reminder to take progress photos
Clip or tie up longer hair to show new areas of growth
Save all your photos in a favorites album or wherever you store your photos digitally

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